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Making Sense of Hair Loss

What causes MPHL?

Some men are genetically determined to be particularly sensitive to the effects of a male sex hormone called dihydrotestosterone (DHT) that disrupts the normal pattern of hair growth.9,14,15 In these men, DHT causes the hair follicles to shrink.9 As a result, the growth phase becomes shorter and over time, normal hairs are gradually replaced by finer, downy hairs. Eventually, all that is left is a miniature hair follicle with no hair inside it.10
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